Blood Res.  2023 Sep;58(3):151-155. 10.5045/br.2023.2023120.

Co-existence of RUNX1-RUNX1T1 and BCR-ABL1 in acute myeloid leukemia: a case report

Affiliations
  • 1Department of Laboratory Medicine, Dong-A University College of Medicine, 26 Daesingongwon-ro, Seo-gu, Busan 49201, Korea
  • 2Division of Hematology and Oncology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea


Figure

  • Fig. 1 (A, B) PBS showing blast cells with occasional sharp and singular Auer rod (Wright-Giemsa stain, ×1,000). (C, D) Bone marrow aspiration smear showing blast cells with bread-like nucleus, salmon-colored granules, and occasional single, long, sharp Auer rods (Wright-Giemsa stain, ×1,000).

  • Fig. 2 (A) Agarose gel electro-phoresis of the RT-PCR products showing RUNX1-RUNMX1T1 fusion transcript (size, 197 bp) in lane M4A, and BCR-ABL1 fusion tran-script (size, 320 bp) in M8F lane. (B) Sanger sequencing showing BCR-ABL1, b1a2 (size, 320 bp).


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