Obstet Gynecol Sci.  2023 Sep;66(5):459-461. 10.5468/ogs.23029.

The application of pringle manoeuvre, type three liver mobilisation, full thickness diaphragmatic resection with primary closure technique and peritonectomy in the management of advanced ovarian malignancy

Affiliations
  • 1Department of Gynaecological Oncology, Churchill Cancer Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Abstract


Objective
We present an educational technique for the safe completion of complete cytoreduction of diaphragmatic disease for the management of advanced ovarian malignancy.
Methods
We demonstrated these steps with attention to anatomical landmarks and surgical approaches, considering intraoperative and postoperative morbidity and mortality.
Results
We present the case of a 49-year-old female patient diagnosed with suspected stage 3C ovarian malignancy following diagnostic laparoscopy. We demonstrate the surgical application of the Pringle manoeuvre, type 3 liver mobilisation, and full-thickness diaphragmatic resection. This was completed with a primary closure technique, with integrity ensured through the performance of an air test and Valsalva manoeuvre. Final histology confirmed a serous borderline tumour with invasive implants within a port site nodule (stage 4A).
Conclusion
This technique affirms the essential skills in gynaecological oncology training and details a challenging case requiring advanced surgical skills and knowledge, with specific consideration for intraoperative multidisciplinary decision-making.

Keyword

Diaphragmatic resection; Cytoreduction; Pringle manoeuvre; Peritonectomy; Liver mobilisation

Figure

  • Fig. 1 Advanced energy device excising full thickness diaphragmatic nodules to include pleurectomy, ensuring appropriate macroscopic excision margins.


Reference

References

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3. Harter P, Sehouli J, Lorusso D, Reuss A, Vergote I, Marth C, et al. A randomized trial of lymphadenectomy in patients with advanced ovarian neoplasms. N Engl J Med. 2019; 380:822–32.
4. Soleymani Majd H, Ferrari F, Manek S, Gubbala K, Campanile RG, Hardern K, et al. Diaphragmatic peritonectomy vs. full thickness resection with pleurectomy during visceral-peritoneal debulking (VPD) in 100 consecutive patients with stage IIIC-IV ovarian cancer: a surgical-histological analysis. Gynecol Oncol. 2016; 140:430–5.
5. Addley S, Yao DS, Soleymani Majd H. Primary diaphragmatic closure following diaphragmatic resection and cardiophrenic lymph node dissection during interval debulking surgery for advanced ovarian malignancy. Gynecol Oncol Rep. 2021; 36:100744.
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