J Yeungnam Med Sci.  2023 Jul;40(3):293-296. 10.12701/jyms.2022.00472.

Oral chemical burns caused by topical application of policresulen: a case report

• Chae HS
• Kang S

• KMID: 2544591
• DOI: http://doi.org/10.12701/jyms.2022.00472

Abstract

Oral mucosal burns can occur after contact with various chemical agents, and commonly manifest as areas of mucosal sloughing and ulceration. Policresulen (Albothyl, Celltrion Pharm Inc.) is an over-the-counter topical antiseptic that is frequently used to treat stomatitis. Policresulen solution is highly acidic, with an approximate pH of 0.6; it can thus cause mucosal injury when improperly applied in the oral cavity. Here, we present a rare case of an oral mucosal burn resulting from incorrect self-administration of policresulen and emphasize the importance of increasing understanding of this adverse drug event among consumers and health professionals.

Keyword

Chemical burns; Oral mucosa; Policresulen; Self-treatment

Figure

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  Fig. 1. Clinical photograph shows mucosal ulcer covered with a necrotic, sloughing pseudomembrane in the right maxillary buccal vestibule.

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  Fig. 2. Clinical photograph shows the oral lesion with the maxillary denture in place.

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  Fig. 3. Panoramic radiography demonstrates no remarkable findings.

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  Fig. 4. Clinical photograph shows regression of the lesion following treatment.

Reference

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