J Neurocrit Care.  2023 Jun;16(1):55-57. 10.18700/jnc.220088.

Progressive cerebral large-vessel vasculitis in a patient with Sjögren’s syndrome

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Inje University Busan Paik Hospital, Busan, Korea
  • 2Department of Neurology, Kyung Hee University Hospital, Seoul, Korea
  • 3Department of Neurology, Inje University Busan Paik Hospital, Busan, Korea


Figure

  • Fig. 1. Brain magnetic resonance imaging scans upon admission. (A, B) There were high signal-intensity lesions on diffusion-weighted images in the right middle cerebral artery borderzone area at the right frontal and parietal lobes, and (C, D) relevant lesions were noted on the apparent diffusion coefficient map.

  • Fig. 2. Brain magnetic resonance angiography (MRA) and high-resolution magnetic resonance imaging (MRI) of the carotid plaque. (A) MRA taken 1 year before admission showed no stenosis in both distal internal carotid arteries (ICAs). (B, C) MRA taken upon admission showed moderate to severe stenosis in the right distal ICA (arrowhead). (D, E) On MRA taken 4 days later, severe stenosis was newly discovered in the left distal ICA, proximal M1, and proximal A1 (arrowhead), and (F) focal concentric wall thickening with enhancement at the left distal ICA was confirmed on high-resolution MRI (arrow).


Reference

1. Fox RI. Sjögren's syndrome. Lancet. 2005; 366:321–31.
2. Tobón GJ, Pers JO, Devauchelle-Pensec V, Youinou P. Neurological disorders in primary Sjögren's syndrome. Autoimmune Dis. 2012; 2012:645967.
3. Li JA, Meng HM, Cui ZT, Wang X, Miao J. Recurrent cerebral infarctions in primary Sjögren syndrome: a case report and literature review. Front Neurol. 2018; 9:865.
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