J Korean Ophthalmol Soc.  2023 Jun;64(6):538-544. 10.3341/jkos.2023.64.6.538.

Visual Function after Multifocal Intraocular Lens Insertion in a Heterozygous Granular Corneal Dystrophy Type 2 Patient: Case Report

Affiliations
  • 1Saevit Eye Hospital, Goyang, Korea
  • 26th Medical Company, 6th Marine Brigade, Headquarters Republic of Korea Marine Corps, Incheon, Korea
  • 3Department of Ophthalmology and The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea
  • 4Corneal Dystrophy Research Institute, Yonsei University College of Medicine, Seoul, Korea

Abstract

Purpose
A patient with heterozygous granular corneal dystrophy type 2 (GCD2) underwent phacoemulsification with multifocal intraocular lens insertion, and complained of visual discomfort. We investigated the cause of the discomfort and visual function in this case.
Case summary
A 59-year-old woman with granular opacity had slit lamp photographs taken 5 years earlier. Two years later, she underwent phacoemulsification with multifocal intraocular lens (Trifocal AT Lisa tri toric 839MP®, Carl Zeiss Meditec AG, Inc., Jena, Germany) insertion in both eyes at a local clinic. She felt very uncomfortable after the surgery, but the granular and lattice opacities due to GCD2 of her corneas remained stationary for 5 years. Her visual acuity decreased from preoperatively (preoperative: right 0.5, left 0.6; last visit: right 0.3, left 0.4). Her contrast sensitivity was also decreased and the total higher order aberration was increased (right 1.590 μm, left 1.194 μm), compared to normal range.
Conclusions
Multifocal intraocular lens insertion in cataract surgery can lead to severe declines in contrast sensitivity and visual acuity and increased higher-order aberration in a GCD2 patient. It may not be advisable to use multifocal intraocular lenses in a GCD2 patient.

Keyword

Contrast sensitivity, Corneal wavefront aberration, Granular corneal dystrophy, Multifocal intraocular lens
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