Korean J Transplant.  2022 Nov;36(Supple 1):S96. 10.4285/ATW2022.F-2164.

The effect of a recipient’s body mass index to kidney transplantation outcomes: a retrospective cohort study at National Kidney and Transplant Institute

• Liquete MM
• Duque A

• KMID: 2535612
• DOI: http://doi.org/10.4285/ATW2022.F-2164

Abstract

Background
Studies have shown various outcomes on the effect of body mass index to transplant recipients. Currently, no local study has done to document the results of pre-obese and obese individuals post-kidney transplantation. The study aims to determine the effects of recipients’ body mass index on short-and long-term outcomes after living donor kidney transplantation.
Methods
This is a retrospective cohort study. Body mass index and posttransplant outcomes were measured through chisquare test and ANOVA. The link between body mass index, graft and patient survival was studied using univariate analysis.
Results
Significant difference among recipients’ body mass index and renal graft function was noted in the first week,1 and 6-months, 1 and 3-years post-kidney transplantation. The eGFR levels at the first week, 1 and 6-months were higher in under-weight compared to normal, pre-obese and obese transplant patients. With a P-value of 0.037, link between recipient's body mass index and graft survival after 3 years was noted. Obese patients were three times to experience graft loss compared to pa-tients with normal body mass index (95% OR, 1.03–7.6) at 3 years. Association between body mass index and graft survival oneyear posttransplant was not clearly identified due to small sample size. The same issue with patient survival at 1 and 3-years after kidney transplantation.
Conclusions
Study concludes that pre-obese and obese patients are still viable candidates for kidney transplant. The patient and family should be properly informed about the risks and advantages.