J Korean Ster Func Neurosurg.  2022 Sep;18(2):103-106. 10.52662/jksfn.2022.00241.

Total intravenous anesthesia with remimazolam in a patient with epilepsy who underwent deep brain stimulation: a case report

  • 1Department of Neurology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea
  • 2Department of Anesthesiology and Pain Medicine, Wonju Severance Christian Hospital, Wonju, Korea
  • 3Department of Anesthesiology and Pain Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea


Drugs administered for anesthesia can trigger seizure attacks in patients with epilepsy. Benzodiazepines have been consistently reported to be anticonvulsants, and a novel benzodiazepine, remimazolam, was recently introduced. We report a case of total intravenous anesthesia maintained with remimazolam in a patient with epilepsy who underwent deep brain stimulation of both anterior thalamic nuclei. Despite the administration of multiple anti-epileptic drugs, no tolerance to remimazolam was observed. Perioperative seizures were also not observed. Remimazolam can be considered the anesthetic of choice in patients with epilepsy.


Remimazolam; Intravenous anesthesia; Deep brain stimulation; Epilepsy; case reports
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