Nucl Med Mol Imaging.
2022 Oct;56(5):252-255. 10.1007/s13139-022-00763-5.
The Superiority of 68Ga‑FAPI‑04 over 18F‑FDG in a Case of Gallbladder Cancer
- Affiliations
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- 1Department of Nuclear Medicine, The Affiliated Hospital, Southwest Medical University, Luzhou 646000, Sichuan, People’s Republic of China
- 2Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, No. 25, Taiping St, Luzhou 646000, Sichuan, People’s Republic of China
- KMID: 2534413
- DOI: http://doi.org/10.1007/s13139-022-00763-5
Abstract
- A 56-year-old man presented with vague upper abdominal pain for more than 4 months. His abdominal ultrasound and MRI showed thickening of the neck and base of the gallbladder and nodule formation at the base of the gallbladder. 18F-FDG PET/CT revealed intense FDG uptake in the base of the gallbladder and multiple lymph nodes. 68Ga-FAPI-04 PET/CT not only showed intense FAPI uptake in the above mentioned FDG-avid lesions but also showed intense FAPI uptake in the neck lesion of the gallbladder and some other additional lymph nodes. Finally, histopathological examination confirmed poorly differentiated tubular adenocarcinoma of the neck and base of the gallbladder. Our case illustrated that 68Ga-FAPI-04 PET/CT may outperform 18F-FDG PET/CT in the detection of gallbladder cancer primary and metastatic lesions.
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