Korean J Intern Med.  2022 Jul;37(4):777-785. 10.3904/kjim.2021.427.

Predictors of recurrent acute myocardial infarction despite successful percutaneous coronary intervention

Affiliations
  • 1Department of Cardiology, Chonnam National University Hospital, Gwangju, Korea
  • 2Department of Cardiology, Chonnam National University Medical School, Gwangju, Korea
  • 3Department of Cardiology, Gyeongsang National University College of Medicine, Jinju, Korea
  • 4Department of Cardiology, Kyung Hee University Hospital, Seoul, Korea
  • 5Department of Cardiology, Yeungnam University Medical Center, Daegu, Korea
  • 6Department of Cardiology, Seoul National University Bundang Hospital, Seongnam, Korea
  • 7Department of Cardiology, Keimyung University Dongsan Hospital, Daegu, Korea
  • 8Department of Cardiology, Jeonbuk National University Hospital, Jeonju, Korea
  • 9Department of Cardiology, Pusan National University Hospital, Busan, Korea

Abstract

Background/Aims
Recurrent acute myocardial infarction (AMI) is an adverse cardiac event in patients with a first AMI. The predictors of recurrent AMI after the first AMI in patients who underwent successful percutaneous coronary intervention (PCI) have not been elucidated.
Methods
We analyzed the data collected from 9,869 patients (63.2 ± 12.4 years, men:women = 7,446:2,423) who were enrolled in the Korea Acute Myocardial Infarction Registry-National Institute of Health between November 2011 and October 2015, had suffered their first AMI and had received successful PCI during the index hospitalization. Multivariable logistic regression analysis was performed to identify the independent predictors of recurrent AMI following the first AMI.
Results
The cumulative incidence of recurrent AMI after successful PCI was 3.6% (359/9,869). According to the multivariable logistic regression analysis, the significant predictive factors for recurrent AMI were diabetes mellitus, renal dysfunction, atypical chest pain, and multivessel disease.
Conclusions
In this Korean prospective cohort study, the independent predictors of recurrent AMI after successful PCI for the first AMI were diabetes mellitus, renal dysfunction, atypical chest pain, and multivessel disease.

Keyword

Myocardial infarction; Percutaneous coronary intervention; Risk factors
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