J Korean Soc Laryngol Phoniatr Logoped.
2022 Apr;33(1):26-30. 10.22469/jkslp.2022.33.1.26.
The Benefit of Supplemental Cough Suppression Therapy for Chronic Refractory Cough
- Affiliations
-
- 1Department of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine, Incheon, Korea
- 2Department of Otolaryngology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
- KMID: 2529630
- DOI: http://doi.org/10.22469/jkslp.2022.33.1.26
Abstract
- Background and Objectives
Cough suppression therapy (CST) is a physiotherapy that can be used for patients with chronic refractory cough (CRC). We aimed to investigate the efficacy of CST for CRC. Materials and Method A prospective randomized controlled trial was conducted in 27 patients with CRC. Participants were randomized to receive either standard mucolytic medications for CRC combined with supplemental CST (CST group) or standard medications alone (control group). CST consists of laryngeal hygiene management, humidification, cough suppression technique, breathing method, and counseling. We assessed the symptoms change at baseline and week 4 with the Leicester Cough Questionnaire (LCQ). Secondary efficacy outcomes included the degree of cough Visual Analog Scale (VAS) score (0 to 100 scale).
Results
From 2019 to 2021, 14 CST group patients and 13 control group patients were included. The improvement was significantly greater in the CST group than in the control group for cough VAS score (36.67 to 13.33 vs. 74.29 to 16.43, p<0.001). Patients in the CST group had a significant improvement in total (70.14 to 107.71, p=0.005), physical (31.42 to 43.86, p= 0.015), psychological (23.57 to 40.14, p=0.003), and social (15.14 to 23.71, p=0.005) LCQ scores. However, there was not a significant pre- to post-treatment LCQ score improvement in control group.
Conclusion
CST might be an effective supplemental intervention for CRC.
