J Korean Acad Community Health Nurs.  2022 Mar;33(1):105-113. 10.12799/jkachn.2022.33.1.105.

The Effect of Depression on Quality of Life in Patients with Parkinson's Disease: Mediating Effect of Family Function

Affiliations
  • 1APN, Gerontological Nursing, Suyeong Hyodo Hospital, Busan, Korea
  • 2Assistant Professor, Department of Nursing, Saekyung University, Yeongwol, Korea

Abstract

Purpose
The purpose of this study is to explore the roles and function of family in mediating the relationship between depression and quality of life of patients with Parkinson’s disease (PD). Most studies have found that depression is particularly common in patients with PD and further associated with poor quality of life. Family function, as a mediator, is based on a strength orientation perspective that emphasizes not only their responsibilities and risks but also recuperative powers and growth potential.
Methods
Overall 157 adults with idiopathic Parkinson’s disease were enrolled in this study via outpatient clinic and completed a set of assessment to measure depression using BDI, family APGAR questionnaire, and patients’ quality of life using PDQ-8. Hierarchical multiple regression analysis was conducted to examine the mediating role of family APGAR score in the relationship between BDI and PDQ-8.
Results
Patients' depression, gait disturbance, duration of illness, and family function were statistically significant on quality of life. These factors accounted for 60% of the variance in quality of life. Family function has a partial mediating effect on the relationship between depression and quality of life.
Conclusion
Findings from the study suggest that although PD patients' depression impacts their quality of life, by having strong family function, the extent to which depression impacts the quality of life can be favorably mitigated. Additionally, these outcomes have important implications for future model development regarding PD patients.

Keyword

Parkinson disease; Quality of life; Depression; Family
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