J Korean Soc Radiol.
2022 Jan;83(1):3-27. 10.3348/jksr.2021.0177.
Beyond Coronary CT Angiography: CT Fractional Flow Reserve and Perfusion
- Affiliations
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- 1Department of Radiology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea
- 2Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- 3Department of Radiology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea
- 4Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
- KMID: 2525170
- DOI: http://doi.org/10.3348/jksr.2021.0177
Abstract
- Cardiac CT has been proven to provide diagnostic and prognostic evaluation of coronary artery disease for cardiovascular risk stratification and treatment decision-making based on rapid technological development and various research evidence. Coronary CT angiography has emerged as a gateway test for coronary artery disease that can reduce invasive angiography due to its high negative predictive value, but the diagnostic specificity is relatively low. However, coronary CT angiography is likely to overcome its limitations through functional evaluation to identify the hemodynamic significance of coronary artery disease by analyzing myocardial perfusion and fractional flow reserve through cardiac CT. Recently, studies have been actively conducted to incorporate artificial intelligence to make this more objective and reproducible. In this review, functional imaging techniques of cardiac computerized tomography are explored.
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