Neonatal Med.  2021 Nov;28(4):153-156. 10.5385/nm.2021.28.4.153.

Human Herpesvirus 6 Meningitis in a Neonatal Case

  • 1Department of Pediatrics, Kosin University College of Medicine, Busan, Korea


Incidence of human herpesvirus-6 (HHV-6) infection in the neonatal period has been reported in few cases. HHV-6, commonly responsible for roseola, is known to establish infection during infancy and early childhood. A 14-day-old neonate, presented with a fever of 38.3℃, primarily due to an HHV-6 infection, was admitted to our neonatal intensive care unit. A polymerase chain reaction (PCR) of his cerebrospinal fluid was positive for HHV-6. Additionally, serology for HHV-6 PCR was positive. We believe that HHV-6 can cause infection in febrile newborn infants.


Herpesvirus 6, human; Meningitis; Infant, newborn


  • Figure 1. Hospital course of patient. Abbreviations: HD, hospital day; HS-CRP, high sensitivity C-reactive protein; CSF, cerebrospinal fluid; MRI, magnetic resonance imaging; PCR, polymerase chain reaction; HHV-6, human herpesvirus-6.


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