J Korean Ophthalmol Soc.  2021 Nov;62(11):1509-1517. 10.3341/jkos.2021.62.11.1509.

Short-term Safety Evaluation of Resident-performed Intravitreal Injection

Affiliations
  • 1Department of Ophthalmology, Hallym University College of Medicine, Seoul, Korea
  • 2Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea

Abstract

Purpose
This study evaluated the short-term safety of resident-performed intravitreal injections.
Methods
We retrospectively reviewed the medical records of 503 patients (503 eyes) treated for the first time in our hospital from January 2018 to October 2020 via intravitreal bevacizumab, ranibizumab, aflibercept, or triamcinolone acetonide injections by residents or retina specialists. In terms of short-term ophthalmic complications, patients were followed-up 1 day, 1 week, and 1 month after injection.
Results
A total of 503 eyes of 503 patients were included. Intravitreal injections were given to 211 and 292 eyes by residents (the resident group) and retina specialists (the retina specialist group), respectively. There were no between-group differences in baseline characteristics except in terms of the indications for injection. Intraocular pressure elevation >5 mmHg occurred in two eyes (0.95%) in the resident group and five (1.71%) in the retina specialist group, but the difference was not statistically significant. Subconjunctival hemorrhage occurred in 29 eyes (13.74%) of the resident group and 32 eyes (10.96%) of the retina specialist group; again, the difference was not statistically significant. No case of noninfectious endophthalmitis occurred in the resident group but two (0.68%) cases occurred in the retina specialist group; again, the difference was not significant. There were two (0.95%) cases of infectious endophthalmitis in the resident group and one (0.34%) case in the retina specialist group; again, the difference was not significant. No corneal erosion, traumatic lens damage, vitreous hemorrhage, or retinal tearing or detachment were noted in either group.
Conclusions
Resident-performed intravitreal injections appear to be safe.

Keyword

Intravitreal injection, Resident performed, Short term safety
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