Ann Clin Neurophysiol.  2021 Oct;23(2):117-120. 10.14253/acn.2021.23.2.117.

Autonomic instability in severe tetanus: a case report

• Seo SW
• Lee J
• Yoo BG
• Kim J
• Huh SY

• KMID: 2521889
• DOI: http://doi.org/10.14253/acn.2021.23.2.117

Abstract

Tetanus is an infectious disease of the nervous system caused by Clostridium tetani, and is characterized by tonic muscle contractions, painful spasms, and autonomic dysfunction. Severe autonomic dysfunction associated with tetanus can be life-threatening. We present a 62-year-old female who experienced lockjaw after an ankle fracture. The patient was diagnosed with tetanus and received tetanus immunoglobulin and a vaccination. The patient subsequently experienced labile hypertension. This case highlights the challenge and importance of managing cardiovascular instability.

Figure

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  Fig. 1. Schematic diagram of changes in the blood pressure of the patient, the period of medical treatment, and the maximum (max), minimum (min), and mean arterial blood pressures over a 40-day period. Blood pressure fluctuation persisted despite 3 weeks of treatment and decreased gradually thereafter. SBP, systolic blood pressure; DBP, diastolic blood pressure.

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