Korean J Med Hist.  2021 Aug;30(2):317-354. 10.13081/kjmh.2021.30.317.

Localization of Praziquantel Production and Clonorchiasis Control Program in Korea, 1970s~1980s

• PARK J
• JUNG J

• KMID: 2520926
• DOI: http://doi.org/10.13081/kjmh.2021.30.317

Abstract

The Korean parasite control program is regarded as one of the most successful examples of health care movement in Korea. This ‘Parasite Eradication Program’ which was conducted from 1969 to 1995, involved testing and treating of 300 million people. In cooperation with Japan, parasitologists and activists who participated in the parasite control program formed a common system called the ‘Mass Testing, Mass Treatment.’ This study focuses on the localization process of Praziquantel, Clonorchiasis treatment production and its application in Clonorchiasis control program. Parasitologists rapidly introduced newly developed Praziquantel, and Korean chemists quickly reverse engineered the compound to evade patent issues. This allowed for the mass production of Praziquantel at a lower price, which in turn enabled a nationwide Clonorchiasis control program. At the same time, low price and stable supply opened the private market for Praziquantel. However, acceptance and understanding of the Praziquantel differed significantly among the stakeholders. For the government, it was a means for policy propaganda, and for the health agencies, it was a means for mass scale control program, while for the public, it was a means for maintaining conventional eating habits without risk of infection. This study reveals how the material end of a disease control policy is accepted and interpreted by different actors.

Keyword

Praziqauntel; Clonorchis sinensis; Pharmaceutical; Localization; Localization; Reverse Engineering; Reverse Engineering; Patent; Patent; Parasite Control Program; Parasite Control Program