J Rhinol.  2021 Jul;28(2):125-129. 10.18787/jr.2021.00354.

A Case of Schwannoma in Subfrontal Area and Nasal Cavity

• Jung NY
• Heo JW
• Han SH
• Bae WY

• KMID: 2518680
• DOI: http://doi.org/10.18787/jr.2021.00354

Abstract

Schwannoma is a benign solitary neoplasm emerging from the Schwann cells of the peripheral, cranial and autonomic nerves. Approximately 25 to 45% of schwannomas occur in the head and neck region. However, schwannoma in the subfrontal area, nasal cavity or paranasal sinus is very rare and accounts for only 4% of these neoplasms. We experienced a case of schwannoma in the subfrontal area and left nasal cavity in a 74-year-old man who complained of recurrent rhinorrhea. We report this unusual case of schwannoma with a review of the literature.

Keyword

SchwannomaㆍNasal cavityㆍNeurilemmoma; 신경초종·비강·신경집종

Figure

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  Fig. 1. Preoperative nasal endoscopy shows a yellowish, smooth surfaced mass between the nasal septum and the left inferior turbinate. S: Nasal septum, IT: Inferior turbinate.

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  Fig. 2. Preoperative CT scan shows about 2×5.5 cm sized expansile mass in left nasal cavity involving both frontal sinus, anterior cranial fossa, frontal base.

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  Fig. 3. Brain magnetic resonance images (MRI). Coronal T1-weighted scan (A) and T2-weighted scan (B) show ill-defined inhomogeneous mass of intermediate signal intensity in nasal cavity, frontal sinus, frontal base and left maxillary sinus.

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  Fig. 4. Histopathologic finding of schwannoma. A well-encapsulated tumor shows areas of dense (astrix) and loose cellular population (arrowhead) (×50) (A). Tumor cells are showing Antoni A areas with classic spindle shaped cells and and elongated palisading nuclei which is called Verocay body (black arrow) and hypocellular Antoni B areas (white arrow) (×200) (B) and immunoreactive for S-100 protein (×200) (C).

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  Fig. 5. Post-operative findings. Endoscopic exam shows well healing state of the nasal cavity 2 months after the operation (A). Postoperative MRI shows no sign of recurrence or remnant tumor (B).

Reference

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