J Korean Soc Radiol.  2021 Jul;82(4):770-790. 10.3348/jksr.2021.0072.

Update in Diagnosis of Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormality

  • 1Department of Radiology, Soonchunhyang University Seoul Hospital, Seoul, Korea


Idiopathic pulmonary fibrosis (IPF), based on the 2018 international clinical practice guidelines, can be diagnosed with a usual interstitial pneumonia (UIP) pattern on high-resolution computed tomography (HRCT) and compatible clinical findings. Given that imaging is pivotal for IPF evaluation and diagnosis, more emphasis should be placed on the integration of clinical, radiological, and pathologic findings for multidisciplinary diagnosis. Interstitial lung abnormality (ILA), on the other hand, has a purely radiological definition based on the incidental identification of CT abnormalities. Taken together, differentiation between ILA and clinically significant interstitial lung disease (ILD) must be based on proper clinical evaluation. With this review, the recent updates in IPF diagnosis and the radiologic considerations for ILA can be well understood, which can be helpful for the proper diagnosis and management of patients with diffuse interstitial pulmonary fibrosis.


Idiopathic Pulmonary Fibrosis; Idiopathic Interstitial Pneumonias; Lung Diseases; Interstitial; Tomography; X-Ray Computed
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