J Vet Sci.  2021 May;22(3):e44. 10.4142/jvs.2021.22.e44.

Intraoperative fluid therapy for videoassisted ovariohysterectomy in dogs

• Oliveira MTd
• Scussel Feranti JP
• Coradini GP
• Chaves RO
• Corrêa LFD
• Linhares MT
• Thiesen R
• Machado Silva MA
• Brun MV

• KMID: 2516202
• DOI: http://doi.org/10.4142/jvs.2021.22.e44

Abstract

Background
Intraoperative fluids are still poorly studied in veterinary medicine. In humans the dosage is associated with significant differences in postoperative outcomes.
Objectives
The aim of this study is to verify the influence of three different fluid therapy rates in dogs undergoing video-assisted ovariohysterectomy.
Methods
Twenty-four female dogs were distributed into three groups: G5, G10, and G20. Each group was given 5, 10, and 20 mL·kg ⁻¹ ·h ⁻¹ of Lactate Ringer, respectively. This study evaluated the following parameters: central venous pressure, arterial blood pressure, heart rate, respiratory rate, temperature, acid-base balance, and serum lactate levels. Additionally, this study evaluated the following urinary variables: urea, creatinine, protein to creatinine ratio, urine output, and urine specific gravity. The dogs were evaluated up to 26 h after the procedure.
Results
All animals presented respiratory acidosis during the intraoperative period. The G5 group evidenced intraoperative oliguria (0.80 ± 0.38 mL·kg⁻¹ ·h⁻¹ ), differing from the G20 group (2.17 ± 0.52 mL·kg ⁻¹ ·h ⁻¹) (p = 0.001). Serum lactate was different between groups during extubation (p = 0.036), with higher values being recorded in the G5 group (2.19 ± 1.65 mmol/L). Animals from the G20 group presented more severe hypothermia at the end of the procedure (35.93 ± 0.61°C) (p = 0.032). Only the members of the G20 group presented mean potassium values below the reference for the species. Anion gap values were lower in the G20 group when compared to the G5 and G10 groups (p = 0.017).
Conclusions
The use of lactated Ringer's solution at the rate of 10 mL·kg ⁻¹ ·h ⁻¹ seems to be beneficial in the elective laparoscopic procedures over the 5 or 20 mL·kg⁻¹ ·h⁻¹ rates of infusion.

Keyword

Dogs; crystalloids; lactated Ringer's solution; videosurgery; abdominal perfusion pressure