J Korean Ophthalmol Soc.  2020 Nov;61(11):1386-1390. 10.3341/jkos.2020.61.11.1386.

Behçet’s Disease Initially Presenting as a Macular Hole with Exudative Retinal Detachment

  • 1Department of Ophthalmology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea


To report a case of Behçet’s disease presenting as a macular hole with exudative retinal detachment and an examination of its mechanism.
Case summary
A 19-year-old woman presented with decreased visual acuity in her right eye for a month. The visual acuity of the right eye was finger count. Inflammation was evident in the anterior chamber cells and vitreous. Optical coherence tomography revealed a macular hole with retinal detachment. Retinal vasculitis was observed in fluorescein angiography imagery. Vasculitis was well controlled with administration of 1 mg per kg oral prednisolone. Vitrectomy and internal limiting membrane (ILM) peeling were performed with ILM flap creation. The macular hole was closed after the surgery. Behçet’s disease was diagnosed based on a manifestation of genital and oral ulcers during tapering of prednisolone. Subcutaneous adalimumab has been used to control uveitis due to repeated relapse.
This is a case of Behçet’s disease initially presenting as macular hole retinal detachment. Uveitis such as that occurring with Behçet’s disease should be considered if the macular hole retinal detachment is noticed in a young patient without posterior staphyloma.


Behçet’s disease; Macular hole retinal detachment; Uveitis
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