Obstet Gynecol Sci.
2020 Nov;63(6):750-752. 10.5468/ogs.20088.
Radiation induced pemphigoid disease
- Affiliations
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- 1Department of Obstetrics and Gynecology, Presbyterian Medical Center, Jeonju, Korea
- KMID: 2511217
- DOI: http://doi.org/10.5468/ogs.20088
Abstract
- Among the possible complications of radiation therapy, acute and chronic side effects on the skin can be induced by percutaneous radiotherapy in the target site. Common skin lesions include radiation dermatitis, which can be treated by topical application of dressing and ointment. Pemphigoid disease, which displays similar clinical features as other skin diseases such as recurrent cancer and herpes zoster, rarely occurs in the site of radiotherapy; therefore, care must be taken during diagnosis for a timely treatment. The present report is a case of pemphigoid disease that had developed in a patient with endometrioid/clear cell carcinoma after radiation therapy, and the time between onset and radiotherapy was more than 6 months.
Keyword
Figure
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Fig. 1. On hospital day 4, diffuse and erythematous bullae size worsened in the right thigh. We only applied acyclovir cream on the lesion.
Fig. 2. After administering prednisolone and antibiotics, inflamed area healed and erythema did not spread.
Reference
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References
1. Shon W, Wada DA, Kalaaji AN. Radiation-induced pemphigus or pemphigoid disease in 3 patients with distinct underlying malignancies. Cutis. 2016; 97:219–22.2. Isohashi F, Konishi K, Umegaki N, Tanei T, Koizumi M, Yoshioka Y. A case of bullous pemphigoid exacerbated by irradiation after breast conservative radiotherapy. Jpn J Clin Oncol. 2011; 41:811–3.
Article3. Mul VE, van Geest AJ, Pijls-Johannesma MC, Theys J, Verschueren TA, Jager JJ, et al. Radiation-induced bullous pemphigoid: a systematic review of an unusual radiation side effect. Radiother Oncol. 2007; 82:5–9.
Article4. Parikh SK, Ravi A, Kuo DY, Nori D. Bullous pemphigoid masquerading as acute radiation dermatitis: case report. Eur J Gynaecol Oncol. 2001; 22:322–4.5. Nguyen T, Kwan JM, Ahmed AR. Relationship between radiation therapy and bullous pemphigoid. Dermatology. 2014; 229:88–96.
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