J Cerebrovasc Endovasc Neurosurg.
2020 Dec;22(4):267-272. 10.7461/jcen.2020.E2019.09.006.
Foreign body granuloma reaction after endovascular therapy of an unruptured right frontal arteriovenous malformation
- Affiliations
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- 1Department of Surgery-Neurosurgery, Arzobispo Loayza National Hospital, Lima, Peru
- 2Department of Neurosurgery, Umberto I General Hospital, Università Politecnica delle Marche, Ancona, Italy
- 3Department of Neurosurgery, Ospedali Riuniti Marche Nord, Pesaro, Italy
- 4Department of Pathology, Alberto Hurtado School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru
- 5Department of Neurosurgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland
- KMID: 2511040
- DOI: http://doi.org/10.7461/jcen.2020.E2019.09.006
Abstract
- Foreign body reactions after endovascular procedures for brain arteriovenous malformations are extremely rare. We report the case of a cerebral foreign body granuloma reaction after embolization of a frontal arteriovenous malformation with Onyx. A previously treated 36-year-old man underwent re-embolization of a residual and recurrent unruptured right frontal vascular malformation with Onyx. The post-procedural imaging revealed a right frontotemporal heterogeneously enhancing expansive lesion associated with a residual malformation. Following microsurgical resection, the histopathological examination of the expansive lesion revealed basophilic foreign body like deposits adjacent to multi-nucleated giant cells, highly compatible with cerebral foreign body granulomas reaction to Onyx. The clinical and radiological follow-up of the patient was favorable after complete resection of the lesions.
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