Nucl Med Mol Imaging.  2020 Oct;54(5):224-232. 10.1007/s13139-020-00654-7.

Recent Survey of Effective Doses of F-18 FDG Torso PET/CT in Korea and the Current Recommendations for CT Protocols of PET/CT

Affiliations
  • 1Department of Nuclear Medicine, Chosun University Hospital, Gwangju, South Korea
  • 2Department of Nuclear Medicine, Soonchunhyang University Bucheon Hospital, Bucheon-si, Gyeonggi-do, Republic of Korea
  • 3Department of Nuclear Medicine, Pusan National University Hospital, Busan, South Korea
  • 4Department of Nuclear Medicine, Asan Medical Center, Seoul, South Korea
  • 5Department of Nuclear Medicine, Korea University Anam Hospital, Seoul, South Korea
  • 6Department of Nuclear Medicine, Korea University Medical Center, Korea University College of Medicine, Seoul, South Korea
  • 7Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
  • 8Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Republic of Korea
  • 9Department of Nuclear Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, South Korea
  • 10Department of Nuclear Medicine, Korea University Guro Hospital, Seoul, South Korea
  • 11Department of Nuclear Medicine, Hanyang University Guri Hospital, Guri-si, South Korea
  • 12Department of Nuclear Medicine, Ajou University Medical Center, Suwon, South Korea
  • 13Division of Applied RI, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea
  • 14Department of Nuclear Medicine, Chungnam National University Hospital, Daejeon, South Korea
  • 15Department of Nuclear Medicine, National Cancer Center, Goyang-si, South Korea

Abstract

Purpose
This study aimed to construct a database of the effective doses (ED) from F-18 fluorodeoxyglucose (FDG) torso positron emission tomography/computed tomography (PET/CT) in Korea to provide data that supports the reduction of the CT dose of PET/CT and optimization of PET/CT protocols in Korea.
Methods
We investigated data of ED and CT parameters of FDG PET/CT. The data were analyzed by body weight groups.
Results
A total of 31 hospitals participated in the survey (99 adults). The mean total EDs (± SD) were 8.77 ± 2.76, 10.93 ± 3.14, and 12.57 ± 3.79 mSv for the 55-, 70-, and 85-kg groups, respectively. The FDG EDs were 4.80 ± 0.98, 6.05 ± 1.15, and 6.89 ± 1.52 mSv, and the CT EDs were 4.00 ± 2.12, 4.88 ± 2.51, and 5.68 ± 2.89 mSv, respectively. Of the enrolled hospitals, 54.5% used ultra-low-dose CT protocols, and their CT ED was significantly lower than low-dose CT group in all groups (2.9 ± 1.0, 3.2 ± 1.1, and 3.3 ± 1.0 mSv vs. 6.6 ± 1.6, 7.2 ± 2.1, and 7.9 ± 2.2 mSv, all p < 0.001, respectively). In the ultra-low-dose CT group, the CT ED with the iterative reconstruction was significantly lower than that of CT without iterative reconstruction in the 55-kg group (2.4 ± 0.9 vs. 3.3 ± 0.9, p = 0.04).
Conclusions
These results and current recommendations can be helpful for optimizing PET/CT diagnostic reference level (DRL) and reducing unnecessary PET/CT radiation exposure.

Keyword

PET/CT; CT; Effective dose; 18F-FDG; Guidelines
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