J Clin Neurol.  2020 Oct;16(4):612-623. 10.3988/jcn.2020.16.4.612.

Effects of Multicomponent Exercise on Cognitive Function in Elderly Korean Individuals

Affiliations
  • 1Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
  • 2Department of Health Care and Science, Dong-A University College of Medicine, Busan, Korea
  • 3Institute of Convergence Bio-Health, Dong-A University College of Medicine, Busan, Korea
  • 4Department of Neurology, Dong-A University College of Medicine, Busan, Korea
  • 5Department of Family Medicine, Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
  • 6Department of Public Health, College of Medicine, Catholic University, Seoul, Korea
  • 7Department of Neurology, College of Medicine, Korea University, Seoul, Korea
  • 8Department of Neurology, Hanyang University College of Medicine, Seoul, Korea
  • 9Department of Neurology, Seongnam Center of Senior Health, Seongnam, Korea
  • 10Department of Neurology, Bobath Memorial Hospital, Seongnam, Korea

Abstract

Background and Purpose
The aim of this study was to investigate the effects of multicomponent exercise on cognitive function, depression, and quality of life in elderly individuals.
Methods
This study prospectively recruited 605 participants, and constructed an exercise pyramid comprising even distributions of daily physical activities, aerobic exercise, musclestrengthening exercise, flexibility exercise, balance exercise, and activities that subjects could perform while sitting down. The exercise program was divided into six stages according to the participant’s level of frailty. The 12-week exercise program intervention was conducted once yearly.
Results
The exercise regimen was followed by 402 of the 605 enrolled participants, giving a dropout rate of 33.6%. The 27-month exercise program was completed by 60 participants. The scores for the Mini Mental State Examination for dementia screening (MMSE-DS), short form of the Geriatric Depression Scale, World Health Organization Quality of Life Assessment (WHOQOL-BREF), International Physical Activity Questionnaire (IPAQ), fear of falling, handgrip strength, and walking speed were improved after the exercise intervention. The analysis of frailty revealed that participants in the frail group showed greater improvements for the MMSE-DS, WHOQOL-BREF, IPAQ, fear of falling, handgrip strength, and walking speed.
Conclusions
Individually customized, multicomponent exercise programs lead to improved levels of cognitive function, depression, and quality of life, especially among those who are more frail.

Keyword

exercise; cognition; quality of life
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