Obstet Gynecol Sci.  2020 Jul;63(4):543-547. 10.5468/ogs.19189.

Granulomatous peritonitis caused by iatrogenic spillage of ovarian dermoid cystectomy: a case report and literature review

Affiliations
  • 1Department of Obstetrics and Gynecology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
  • 2Department of Obstetrics and Gynecology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea

Abstract

A 39-year-old nulliparous woman experienced continuous mild fever and abdominal pain since undergoing laparoscopic ovarian dermoid cystectomy 3 months previously in a local hospital. Abdominal computed tomography revealed diffuse heterogeneous fat infiltrations with numerous micronodules in the greater and lesser omentum, combined with ascites with thickening of the parietal peritoneum. The patient underwent exploratory laparoscopy, which included partial pelvic peritonectomy, excision of granulomas, and adhesiolysis with massive irrigation. The patient was treated successfully with laparoscopic surgery and all reproductive structures were spared without operative complications. To avoid peritonitis, complete removal of cyst contents and massive irrigation should be performed during ovarian dermoid cystectomy. Conservative surgical treatment may be a good choice for treating granulomatous peritonitis induced by iatrogenic rupture.

Keyword

Iatrogenic disease; Teratoma, ovarian; Peritonitis

Figure

  • Fig. 1. Preoperative abdominopelvic computed tomography (CT) findings and intraoperative findings of granulomatous peritonitis. (A) Preoperative CT revealing diffuse moderate heterogeneous, smudged fat infiltrations with numerous micronodules in the greater and lesser omentum, combined with diffuse mild ascites with diffuse thickening of the parietal peritoneum, with tubular enhancing granulation tissue in the right lower quadrant abdominal wall. (B) Laparoscopic view revealing profuse sebaceous material in the entire pelvic cavity. (C) Laparoscopic view revealing multiple nodular lesions in the greater and lesser omentum.

  • Fig. 2. Histological findings of peritoneal nodules. (A) Chronic inflammation and fibrosis of the omentum (hematoxylin and eosin [H&E] staining, original magnification ×40). (B) Hair follicle-like structure in the omentum (H&E staining, original magnification ×200). (C) Damaged hair follicle-like structure with multinucleated giant cells (H&E staining, original magnification ×200). (D) Foreign-body type granuloma (H&E staining, original magnification ×200).


Reference

References

1. Comerci JT Jr, Licciardi F, Bergh PA, Gregori C, Breen JL. Mature cystic teratoma: a clinicopathologic evaluation of 517 cases and review of the literature. Obstet Gynecol. 1994; 84:22–8.
2. Shamshirsaz AA, Shamshirsaz AA, Vibhakar JL, Broadwell C, Van Voorhis BJ. Laparoscopic management of chemical peritonitis caused by dermoid cyst spillage. JSLS. 2011; 15:403–5.
Article
3. Huss M, Lafay-Pillet MC, Lecuru F, Ruscillo MM, Chevalier JM, Vildé F, et al. Granulomatous peritonitis after laparoscopic surgery of an ovarian dermoid cyst. Diagnosis, management, prevention, a case report. J Gynecol Obstet Biol Reprod (Paris). 1996; 25:365–72.
4. Clément D, Barranger E, Benchimol Y, Uzan S. Chemical peritonitis: a rare complication of an iatrogenic ovarian dermoid cyst rupture. Surg Endosc. 2003; 17:658.
5. Kaya M, Kaplan MA, Isikdogan A, Celik Y. Differentiation of tuberculous peritonitis from peritonitis carcinomatosa without surgical intervention. Saudi J Gastroenterol. 2011; 17:312–7.
Article
6. Shawki O, Ramadan A, Askalany A, Bahnassi A. Laparoscopic management of ovarian dermoid cysts: potential fear of dermoid spill, myths and facts. Gynecol Surg. 2007; 4:255–60.
Article
7. Phupong V, Sueblinvong T, Triratanachat S. Ovarian teratoma with diffused peritoneal reactions mimicking advanced ovarian malignancy. Arch Gynecol Obstet. 2004; 270:189–91.
Article
8. Suprasert P, Khunamornpong S, Siriaunkgul S, Phongnarisorn C, Siriaree S. Ruptured mature cystic teratomas mimicking advanced stage ovarian cancer: a report of 2 cases study. J Med Assoc Thai. 2004; 87:1522–5.
9. Mas MR, Cömert B, Sağlamkaya U, Yamanel L, Kuzhan O, Ateşkan U, et al. CA-125; a new marker for diagnosis and follow-up of patients with tuberculous peritonitis. Dig Liver Dis. 2000; 32:595–7.
Article
10. Stuart GC, Smith JP. Ruptured benign cystic teratomas mimicking gynecologic malignancy. Gynecol Oncol. 1983; 16:139–43.
Article
11. Royal College of Obstetricians and Gynaecologists (UK). Management of adnexal masses in premenopausal women. Green-top guidelines No. 62. London: Royal College of Obstetricians and Gynaecologists;2011.
12. Fielder EP, Guzick DS, Guido R, Kanbour-Shakir A, Krasnow JS. Adhesion formation from release of dermoid contents in the peritoneal cavity and effect of copious lavage: a prospective, randomized, blinded, controlled study in a rabbit model. Fertil Steril. 1996; 65:852–9.
13. Kondo W, Bourdel N, Cotte B, Tran X, Botchorishvili R, Jardon K, et al. Does prevention of intraperitoneal spillage when removing a dermoid cyst prevent granulomatous peritonitis? BJOG. 2010; 117:1027–30.
Article
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