Perinatology.  2020 Jun;31(2):103-107. 10.14734/PN.2020.31.2.103.

Preterm Delivery due to Listeriosis in Third Trimester Pregnancy

  • 1Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea


Listeria monocytogenes is a ubiquitous pathogen in the environment, capable of causing human and animal infection. Listeriosis is predominantly a foodborne illness caused by consumption of food contaminated with listeria. Listeriosis in pregnancy can cause miscarriage, stillbirth and preterm labor. Listeria monocytogenes is the causative agent of serious infection such as meningoencephalitis and septicemia with about 25% mortality rate. The frequency is as high as 50% in neonates. We experienced a case of listeriosis in a singleton pregnancy at 28rd week of gestation that presented with fever, chill, lower abdominal pain, and eventually resulted in fetal distress and we finally performed emergency cesarean section. Pathologic results of the placenta, as well as blood and amniotic fluid culture of the mother confirmed Listeria monocytogenes infection. Neonatal blood culture also confirmed Listeria monocytogenes infection and neonate presents septicaemia, respiratory distress and granulomatosis infantisepticum. High-dose ampicillin, imipenem, cilastatin was used to Neonate and improved neonatal outcome and discharged.


Listeria monocytogenes; Fetal distress; Cesarean section
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