Precis Future Med.  2020 Jun;4(2):60-68. 10.23838/pfm.2020.00016.

Comparison of oncological outcomes of single-port versus multi-port video-assisted thoracoscopic surgery for non-small-cell lung cancer: a propensity-matched analysis

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Armed Forces Capital Hospital, Seongnam, Korea
  • 2Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
  • 3Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Abstract

Purpose
There are few reports about oncological outcomes of single-port (SP) video-assisted thoracoscopic surgery (VATS) lobectomy, represented by overall survival (OS), disease-free survival (DFS), and adequacy of lymph node retrieval. We designed this study to analyze the oncological outcomes of SP versus multi-port (MP) VATS lobectomy for non-small-cell lung cancer (NSCLC).
Methods
From January 2012 to February 2014, 243 consecutive patients undergoing VATS lobectomy for NSCLC were enrolled. Intention-to-treat analysis with propensity score matching was conducted to compare the oncological outcomes between SP and MP VATS lobectomy for NSCLC.
Results
Seventy-three patients underwent SP VATS lobectomy, and 154 patients underwent conventional MP VATS lobectomy. Propensity score matching created 63 patients in each group. The median follow-up was 65.8 and 72.5 months in the SP and MP VATS groups, respectively. No significant differences were observed in the number of resected lymph nodes (14.6 vs. 16.1, P= 0.329), number of resected mediastinal lymph node stations (2.3 vs. 2.5, P= 0.091), and postoperative complications. The OS at 5 years was 89.9% and 86.9% in the SP and MP VATS groups, respectively (log-rank test, P= 0.344). The DFS at 5 years was 75.1% and 75.7% in the SP and MP VATS groups, respectively (log-rank test, P= 0.899).
Conclusion
There were no significant differences in oncological outcomes of SP VATS lobectomy for NSCLC and those of MP VATS lobectomy.

Keyword

Carcinoma, non-small-cell lung; Thoracic surgery, video-assisted; Survival rate
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