Korean J Parasitol.  2020 Apr;58(2):129-134. 10.3347/kjp.2020.58.2.129.

Dientamoeba fragilis Infection in Patients with Digestive and Non-Digestive Symptoms: A Case-Control Study

  • 1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Saudi Arabia
  • 2Department of Molecular and Clinical Parasitology, National Liver Institute, Menoufia University, Egypt
  • 3Department of Medical Parasitology, Faculty of Medicine, Ain-Shams University, Egypt
  • 4Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Egypt
  • 5Department of Medical Microbiology and Immunology, Faculty of Medicine, Menoufia University, Egypt
  • 6Department of Clinical Pathology, Faculty of Medicine, Menoufia University, Egypt
  • 7Department of Medical Microbiology and Immunology, Faculty of Pharmacy, Taif University, Saudi Arabia


In most developing countries, Dientamoeba fragilis infection is an obscure protozoan infection. We aimed to determine a frequency and clinical importance of D. fragilis infection in Taif, Saudi Arabia. A 1-year case control study included patients with gastrointestinal (cases, n=114) or non-gastrointestinal symptoms (controls, n=90). The fecal samples were examined with the classical parasitological methods for intestinal protozoa, and by real time PCR for D. fragilis. The infection by D. fragilis was detected in 5.8% by PCR and in 4.4% patients by microscopy. The infection was identified more in control group (n=9) than in cases (n=3); a sole infection in 11 patients and mixed with Giardia in 1 patient. The other enteric parasites detected were Blastocystis sp. (8.3%), Giardia sp. (5.3%), Cryptosporidium sp. (2.9%), Entamoeba histolytica (1.4%), Entamoeba coli (0.9%) and Hymenolepis nana (0.4%). Our results tend to reinforce the need to increase awareness of D. fragilis infection in Saudi Arabia.


; diagnosis; microscopy; PCR; Saudi Arabia
Full Text Links
  • KJP
  • Twitter
  • Facebook
Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr