Pediatr Infect Vaccine.  2020 Apr;27(1):69-76. 10.14776/piv.2020.27.e4.

A Case Report of Recurrent Bacterial Meningitis with a Skull Base Abnormality

  • 1Department of Pediatrics, Ewha Womans University Mokdong Hospital, Seoul, the Republic of Korea
  • 2Department of Radiology, Ewha Womans University Mokdong Hospital, Seoul, the Republic of Korea
  • 3Department of Pediatrics, Ewha Womans University College of Medicine, Seoul, the Republic of Korea


Recurrent bacterial meningitis is the reappearance of two or more episodes of meningitis caused by a different or same organism after an intervening period of full convalescence. Predisposing factors for recurrent bacterial meningitis include immunodeficiency and developmental and traumatic anatomical defects. Therefore, careful evaluation of children with recurrent meningitis is essential. We report the case of a patient with a skull base abnormality who had suffered from four events of bacterial meningitis between 8 and 17 years of age. He experienced another event of bacterial meningitis at the age of 21, without undergoing correction for the anatomical defect. Streptococcus agalactiae was identified in the patient's blood and cerebrospinal fluid culture. Afterwards, he underwent surgical treatment for a meningioma; this meningioma was strongly suspected as the cause of the recurrence.


Meningitis; bacterial; Recurrence; Skull base
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