J Vet Sci.  2019 Sep;20(5):e52. 10.4142/jvs.2019.20.e52.

Hypertrophic osteopathy in a cat with cardiac interventricular septal defect

Affiliations
  • 1Setor de Patologia Veterinária, Departamento de Patologia Clínica Veterinária, Faculdade de Veterinária (FAVET), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS 91540-000, Brazil. felipeauatt@gmail.com
  • 2Hospital de Clínicas Veterinárias, Faculdade de Veterinária (FAVET), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS 91540-000, Brazil.

Abstract

A 3-year-old mixed-breed female cat was diagnosed with a ventricular septal defect of the heart through an echocardiogram. After a 9-month treatment, progressive and diffuse hard thickening of all limbs was observed, which on radiographic examinations, revealed a marked thickening of the long bones. The necropsy findings were limited to the appendicular skeleton and thoracic vertebrae, in addition to a severe cardiac interventricular septal defect and lung edema. The histological evaluation revealed severe replacement of the cortical bone by spongy bone in all bone fragments examined. This is the first report of hypertrophic osteopathy occurring in association with a cardiac malformation in a cat.

Keyword

Malformations; congenital disorders; bone diseases; cardiovascular diseases; skeleton

MeSH Terms

Animals
Bone Diseases
Cardiovascular Diseases
Cats*
Child, Preschool
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Edema
Extremities
Female
Heart
Heart Septal Defects, Ventricular
Humans
Lung
Skeleton
Thoracic Vertebrae
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