J Korean Radiol Soc.  1981 Jun;17(1):149-156. 10.3348/jkrs.1981.17.1.149.

An experimental study on radionuclide imaging of bowel infarction using (99m)Tc-pyrophosphate

Abstract

99m Tc-pyrophosphate was investigated for use as an indicator of intestinal infarction in intussusceptedbowel. Irreducible intussusceptions were created in 18 rabbits by surgery. 99mTc-pyrophosphate was then injectedintravenously 6-12, 18, 24 and 30-40 hours later for external scanning. In 15 of the rabbits, infaractiondeveloped with intussusception, and 13 of them demonstrated increased uptake of 99m Tc-pyrophosphate on externalinvivo scintiscans. The remained 2 of them showed no evidence of increased uptake. So false negative cases were2(sensitivity 86.7%). The 3 rabbits without infarction showed no increased uptake of radionuclide. Specimenscanning confirmed increased uptake of radionuclide in the infarcted segments. These observations suggest that 99mTc-pyrophosphate is a reliable indicator of the intestinal infarction that sometimes occures with intestinal intussusception.


MeSH Terms

Infarction*
Intussusception
Rabbits
Radionuclide Imaging*
Technetium Tc 99m Pyrophosphate
Technetium Tc 99m Pyrophosphate
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