J Korean Assoc Oral Maxillofac Surg.  2019 Feb;45(1):43-47. 10.5125/jkaoms.2019.45.1.43.

Nasal septum angiofibroma: a rare condition with an unusual onset

Affiliations
  • 1ENT Clinic, S.M. alle Scotte University Hospital of Siena, Siena, Italy. mariacarla.spinosi@gmail.com
  • 2Institute of Pathologic Anatomy and Histopathology, University of Siena, Siena, Italy.

Abstract

The characteristics of extra-nasopharyngeal angiofibromas tend to be different from angiofibromas of the nasopharynx according to patient gender, patient age, prevalence, affected site, pathogenesis, and clinical and epidemiological features. We report a case of an extra-nasopharyngeal angiofibroma in a 28-year-old man referred to the ENT Clinic for right-sided epistaxis, airflow impairment and nasal swelling. The right nostril was completely occluded works by a reddish-yellow mass that bled easily. The computed tomography scan revealed an "inhomogeneous solid lesion in the nasal fossa". With the patient under general anesthesia, the formation in the anterior portion of the right side of the nasal septum was removed up to its vascular base. Although electrical cauterization efficiently controlled the bleeding, we abraded the sub-perichondral area to prevent further bleeding as well as recurrence. The histological exam report confirmed the diagnosis of angiofibroma. As in our case, epistaxis is commonly the presenting sign of angiofibroma. Yet its onset was peculiar, given that the bleeding started with a low impact trauma. The nasal swelling was also a relevant feature as well as the breathing impairment. Although uncommon, nasal septal angiofibromas should considered in patients with epistaxis.

Keyword

Angiofibroma; Nasal septum; Epistaxis

Figure

  • Fig. 1 Computed tomography scan of the nasal angiofibroma.

  • Fig. 2 Angiofibroma; frontal view.

  • Fig. 3 Angiofibroma; inferolateral view.

  • Fig. 4 Endoscopic view of the nasal fossa after surgical removal of the angiofibroma.

  • Fig. 5 Specimen collection.

  • Fig. 6 Histologic sample (H&E staining, ×5).

  • Fig. 7 Histological sample (CD34 staining, ×5).


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