Chonnam Med J.  2018 Jan;54(1):36-40. 10.4068/cmj.2018.54.1.36.

The Benefits of Resection for Gastric Carcinoma Patients with Non-curative Factors

• Lee JH
• Kim HG
• Ryu SY
• Kim DY

• KMID: 2458583
• DOI: http://doi.org/10.4068/cmj.2018.54.1.36

Abstract

The benefits of resection for gastric carcinoma patients with non-curative factors remain controversial. Thus, we evaluated the survival benefits of resection in these gastric carcinoma patients. We reviewed the hospital records of 467 gastric carcinoma patients with non-curative factors who had resection (n=305) and compared their clinicopathological findings with individuals (n=162) who underwent bypass or exploration from 1996 to 2010. The 3-year survival rate of patients who had resection was higher than was that of patients who did not (13.2 vs. 7.2%, respectively p < 0.001). Cox's proportional hazard regression analysis revealed that only one factor was an independent, statistically significant prognostic parameter: the presence of peritoneal dissemination (risk ratio, 1.37; 95% confidence interval, 1.04-1.79; p < 0.05). The 3-year survival rate of patients with peritoneal dissemination was higher in individuals who underwent resection compared with those who did not (9.5 vs. 4.7%, respectively; p < 0.001). The current results highlight the improved survival rates of gastric carcinoma patients with non-curative factors who underwent surgery compared with those who did not. Although resection is not curative in this group of patients, we still recommend performing the procedure.

Keyword

Stomach Neoplasms; Survival rate; Gastrectomy

MeSH Terms

Gastrectomy
Hospital Records
Humans
Stomach Neoplasms
Survival Rate

Figure

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  FIG. 1 Survival curves of gastric carcinoma patients with non-curative factors who did and did not undergo resection (3-year survival rate: resection, 13.2%; non-resection, 7.2%) (p<0.001).

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  FIG. 2 Survival curves of gastric carcinoma patients with peritoneal dissemination according to the type of operation (3-year survival rate: resection, 9.5%; bypass, 0.0%; exploration, 4.7%) (p<0.001).

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