Korean J Thorac Cardiovasc Surg.  2019 Aug;52(4):195-204. 10.5090/kjtcs.2019.52.4.195.

A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer

Affiliations
  • 1Department of Anesthesiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • 2Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. chkang@snu.ac.kr

Abstract

Lobectomy is considered the standard strategy for early-stage non-small cell lung cancer (NSCLC). However, sublobar resection for NSCLC has recently received increased attention. The objective of this study was to compare 5-year survival, recurrence-free survival, postoperative mortality, and postoperative morbidities in patients who received segmentectomy versus those who received lobectomy through a meta-analysis. Sixteen studies were included and the combined hazard ratios or odds ratios were calculated. The results revealed that the 5-year survival rate after segmentectomy was comparable to that of lobectomy for stage IA NSCLC. However, segmentectomy for stage I NSCLC had lower rates of postoperative mortality and morbidities than lobectomy.

Keyword

Meta-analysis; Non-small-cell lung carcinoma; Lobectomy; Segmentectomy; Survival

MeSH Terms

Carcinoma, Non-Small-Cell Lung*
Humans
Mastectomy, Segmental*
Mortality
Odds Ratio
Survival Rate
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