Ann Clin Neurophysiol.  2019 Jul;21(2):94-97. 10.14253/acn.2019.21.2.94.

Selective impairment of the rapid eye movements in myotonic dystrophy

Affiliations
  • 1Department of Neurology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. lossheaven9@gmail.com

Abstract

The patients with myotonic dystrophy (MD) show ocular motor abnormalities including strabismus, vergence deficits, and inaccurate or slow saccades. Two theories have been proposed to explain the oculomotor deficits in MD. The central theory attributes the defects of eye movements of MD to the involvement of the central nervous system while the muscular theory attributes to dystrophic changes of the extraocular muscles. A 58-year-old woman with MD showed selective slowing of horizontal saccades and reduced peak velocities for both horizontal canals in head impulse tests, while smooth-pursuit eye movements and vertical head impulse responses were normal. This case suggests that the extraocular muscles-as a final common pathway of the voluntary saccade and reflexive vestibular eye movements-may better explain the defective rapid eye movements observed in MD.

Keyword

Head impulse test; Myotonic dystrophy; Saccades

MeSH Terms

Central Nervous System
Eye Movements
Female
Head
Head Impulse Test
Humans
Middle Aged
Muscles
Myotonic Dystrophy*
Reflex
Saccades
Sleep, REM*
Strabismus
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