Korean J Orthod.  2019 Jul;49(4):246-253. 10.4041/kjod.2019.49.4.246.

Effectiveness of caries-preventing agents on initial carious lesions within the scope of orthodontic therapy

Affiliations
  • 1Department of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany. Kyungjin.park@medizin.uni-leipzig.de
  • 2Department of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, Göttingen, Germany.
  • 3Institute for Medical Microbiology, Center for Hygiene and Human Genetics, University Medical Center Göttingen, Göttingen, Germany.

Abstract


OBJECTIVE
To evaluate the effectiveness of three different caries-preventing agents on artificial caries in a Streptococcus mutans-based caries model.
METHODS
Sixty-five caries-free human molar enamel blocks were treated with a demineralization solution and a remineralization solution. The specimens were assigned to the following groups according to the caries-protective product applied: group A, chlorhexidine varnish; group B, fluoride-releasing chemically cured sealant; group C, fluoride-releasing lightcured sealant; group D, positive control (specimens that were subjected to de- and remineralization cycles without treatment with any caries-protective agents); and group E, negative control (specimens that were not subjected to de- and remineralization cycles). Samples in groups A-D were stored in demineralization solution with S. mutans and thereafter in artificial saliva. This procedure was performed for 30 days. Average fluorescence loss (ΔF) and surface size of the lesions were measured using quantitative light-induced fluorescence at baseline and on the 7th, 14th, and 30th days.
RESULTS
After 30 days, group A demonstrated a significant increase in ΔF and the surface size of the lesions, no significant difference in comparison with the positive control group, and a significant difference in comparison with the negative control group. Group B showed no significant changes in both parameters at any of the measurement points. While group C showed increased ΔF after 14 days, no significant fluorescence change was observed after 30 days.
CONCLUSIONS
Both fluoride-releasing sealants (chemically or light-cured) show anti-cariogenic effects, but the use of chlorhexidine varnish for the purpose of caries protection needs to be reconsidered.

Keyword

Cervitec Plus; Maximum Cure; Pro Seal; Quantitative light-induced fluorescence
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