J Vet Sci.  2019 May;20(3):e27. 10.4142/jvs.2019.20.e27.

Pathogenicity of clade H5N6 highly pathogenic avian influenza virus in three chicken breeds from South Korea in 2016/2017

  • 1Laboratory of Pathology, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea. bskims@jbnu.ac.kr
  • 2Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea. bskims@jbnu.ac.kr


In 2016, novel H5N6 highly pathogenic avian influenza virus emerged in Korea. During the outbreak, the virus caused the largest culling, especially in brown chicken lines. We determined the pathogenicity and transmissibility of the virus in 2 white chicken lines of the specific pathogen-free chickens, broilers and brown chicken line of Korean native chicken (KNC). A KNC had a longer virus shedding period and longer mean death time than others. Our study showed that this characteristic in the KNC might have contributed to a farm-to-farm transmission of the brown chicken farms.


Chicken; H5N6; highly pathogenic avian influenza; pathogenicity
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