Ann Dermatol.  2019 Jun;31(3):359-361. 10.5021/ad.2019.31.3.359.

Twenty-Nail Dystrophy Treated with Hydroxychloroquine in a Patient with Alopecia Areata

Affiliations
  • 1Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea. yhwon@chonnam.ac.kr

Abstract

No abstract available.


MeSH Terms

Alopecia Areata*
Alopecia*
Humans
Hydroxychloroquine*
Hydroxychloroquine

Figure

  • Fig. 1 Clinical features of the patient. Scalp (A) showing oval and round, well-circumscribed patches of hair loss with a smooth surface. Finger and toenails showing various degrees of ridging, lack of luster, subungual hyperkeratosis, and brownish discoloration. Before (B, D) and after (C, E) hydroxychloroquine treatment.

  • Fig. 2 Histopathologic analysis of skin biopsy performed at the nail matrix revealing hyperkeratosis, acanthosis, mild spongiosis, epidermal lymphoid cells infiltrates, and vacuolar degeneration of the basal keratinocytes (H&E: A, ×100; B, ×200).


Reference

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