J Korean Soc Radiol.  2019 Jan;80(1):47-58. 10.3348/jksr.2019.80.1.47.

Use of Abbreviated Magnetic Resonance Imaging in Breast Cancer Screening

Affiliations
  • 1Department of Radiology, Seoul National University Hospital, Seoul, Korea. suhyune82@gmail.com

Abstract

Magnetic resonance imaging (MRI) is the most sensitive modality used for breast cancer screening, and is known to detect biologically significant cancers and few interval cancers. Application of standard breast MRI examination is not economical for screening due to the high costs associated with long interpretation and reading times. However, abbreviated breast MRI can reduce time and cost while maintaining diagnostic accuracy, and improve cost-effectiveness in breast cancer screening. A multi-center clinical trial on breast cancer screening using abbreviated breast MRI in high-risk women in Korea is being conducted. Another multicenter clinical trial has been conducted in the USA and Europe to investigate the efficacy of abbreviated breast MRI in women with average to intermediate cancer risk. Furthermore, when performed simultaneously with ultrafast MRI, the accuracy of abbreviated breast MRI can be enhanced. However, since abbreviated breast MRI uses contrast agents, it is important to consider the possibility of residual gadolinium in the body.


MeSH Terms

Breast Neoplasms*
Breast*
Contrast Media
Europe
Female
Gadolinium
Humans
Korea
Magnetic Resonance Imaging*
Mass Screening*
Contrast Media
Gadolinium

Figure

  • Fig. 1. Configuration of standard full diagnostic protocol and abbreviated protocol of breast MRI.

  • Fig. 2. Images of a 39-year-old woman with a history of ductal carcinoma in situ in the left breast and no family history of breast or ovarian cancer. (A) Bilateral full-field digital mammography shows postoperative change only in the left inner breast. (B, C) Maximum-intensity projection (B) and first post-contrast T1-weighted images (C) show segmental clumped non-mass enhancement (arrows) in the right outer breast with underlying moderate background parenchymal enhancement. MRI-guided vacuum-assisted biopsy on the right outer breast shows high-grade ductal carcinoma in situ.

  • Fig. 3. Images of a 61-year-old woman with a history of invasive ductal carcinoma in the left breast and no family history of breast or ovariancancer. Maximum-intensity projection (A) and first post-contrast T1-weighted images (B) show a 0.7-cm oval, circumscribed, heterogeneously enhancing mass in the right breast located at the 7 o'clock position with underlying minimal background parenchymal enhancement. The mass is considered benign because of the high sig-nal intensity on T2-weighted image (C) and stability for over 1 year as compared to the preoperative MRI.


Reference

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