Korean J Otorhinolaryngol-Head Neck Surg.  2019 Mar;62(3):192-196. 10.3342/kjorl-hns.2017.00759.

A Novel Adenomatous Polyposis Coli Gene Mutation of Cribriform-Morular Variant Papillary Thyroid Carcinoma: A Case Report

• Kim HJ
• Choi N
• Chung MK

• KMID: 2442064
• DOI: http://doi.org/10.3342/kjorl-hns.2017.00759

Abstract

Cribriform-morular variant papillary thyroid carcinoma (CMV-PTC) is a rare cancer that may arise in patients with familial adenomatous polyposis (FAP). Adenomatous polyposis coli (APC) gene mutation is associated with FAP, which is known as a premalignant lesion of colon cancer. In this report, we report a 16 years old patient of CMV-PTC comorbid with FAP, which was related with a new type of APC gene mutation.

Keyword

APC gene mutation; Cribriform-morular variant of papillary thyroid carcinoma; Familial adenomatous polyposis

MeSH Terms

Adenomatous Polyposis Coli*
Colonic Neoplasms
Genes, APC
Humans
Thyroid Gland*
Thyroid Neoplasms*