Ann Dermatol.  2019 Apr;31(2):244-246. 10.5021/ad.2019.31.2.244.

A Case of Perinevoid Alopecia on the Scalp

• Kim SM
• Sohng C
• Kim JY
• Jang YH
• Lee SJ
• Lee WJ

• KMID: 2439080
• DOI: http://doi.org/10.5021/ad.2019.31.2.244

Abstract

No abstract available.

MeSH Terms

Alopecia*
Scalp*

Figure

• 

  Fig. 1 (A) A solitary patch of alopecia with a central skin-colored papule on the vertex. (B) Regrowth of hair in the alopecic patch. We received the patient's consent form about publishing all photographic materials.

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  Fig. 2 (A) Numerous nevocytes and a sparse inflammatory cell infiltrate in the papule (H&E, ×40). (B) A hair follicle surrounded by an inflammatory cell infiltrate (H&E, ×100). (C) CD3-positive inflammatory cells of the papule (immunohistochemistry, ×100). (D) CD8-positive inflammatory cells of the papule (immunohistochemistry, ×100). (E) CD3-positive inflammatory cells of the perifollicular area (immunohistochemistry, ×100). (F) CD8-positive inflammatory cells of the perifollicular areas (immunohistochemistry, ×100).

Reference

1. Yesudian P, Thambiah AS. Perinevoid alopecia. An unusual variety of alopecia areata. Arch Dermatol. 1976; 112:1432–1434.

2. Quiroga M, Pecoraro V. Alopecia perinaevica. Hautarzt. 1958; 9:377–378.

3. Bayer-Garner IB, Ivan D, Schwartz MR, Tschen JA. The immunopathology of regression in benign lichenoid keratosis, keratoacanthoma and halo nevus. Clin Med Res. 2004; 2:89–97.

4. Gilhar A, Landau M, Assy B, Shalaginov R, Serafimovich S, Kalish RS. Melanocyte-associated T cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on Prkdc(scid) mice. J Invest Dermatol. 2001; 117:1357–1362.

5. Seol JE, Park IH, Kim DH, Park SH, Kang JN, Kim H, et al. Alopecic and aseptic nodules of the scalp/pseudocyst of the scalp: clinicopathological and therapeutic analyses in 11 Korean patients. Dermatology. 2016; 232:165–170.