Epidemiol Health.  2018;40:e2018003. 10.4178/epih.e2018003.

Rapid qualitative review of ethical issues surrounding healthcare for pregnant women or women of reproductive age in epidemic outbreaks

Affiliations
  • 1Department of Philosophy, University of St Andrews, St Andrews, United Kingdom. pah20@st-andrews.ac.uk
  • 2Ethics and Knowledge, World Health Organization, Geneva, Switzerland.
  • 3Institute of Ethics, History and Theory of Medicine, Ludwig-Maximilians-University Munich, Munich, Germany.

Abstract

This article describes, categorizes, and discusses the results of a rapid literature review aiming to provide an overview of the ethical issues and corresponding solutions surrounding pregnancies in epidemic outbreaks. The review was commissioned by the World Health Organization to inform responses to the Zika outbreak that began in 2015. Due to the urgency of the response efforts that needed to be informed by the literature search, a rapid qualitative review of the literature published in PubMed was conducted. The search and analysis were based on the operationalization of 3 key concepts: ethics, pregnancy, and epidemic outbreak. Ethical issues and solutions were interpreted within a principlist framework. The data were analyzed using qualitative content analysis. The search identified 259 publications, of which the full text of 23 papers was read. Of those, 20 papers contained a substantive part devoted to the topic of interest and were therefore analyzed further. We clustered the ethical issues and solutions around 4 themes: uncertainty, harms, autonomy/liberty, and effectiveness. Recognition of the identified ethical issues and corresponding solutions can inform and improve response efforts, public health planning, policies, and decision-making, as well as the activities of medical staff and counselors who practice before, during, or after an epidemic outbreak that affects pregnant women or those of reproductive age. The rapid review format proved to be useful despite its limited data basis and expedited review process.

Keyword

Ethics; Pregnancy; Epidemics; Reproductive health; Review

MeSH Terms

Counseling
Delivery of Health Care*
Disease Outbreaks*
Ethics*
Female
Humans
Medical Staff
Pregnancy
Pregnant Women*
Public Health
Reproductive Health
Uncertainty
World Health Organization
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