J Korean Soc Emerg Med.  2018 Apr;29(2):236-239. 10.0000/jksem.2018.29.2.236.

Usefulness of phrenic nerve conduction study in early diagnosis of isolated respiratory onset amyotrophic lateral sclerosis

Affiliations
  • 1Department of Emergency Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
  • 2Department of Rehabilitation Medicine, Daegu Fatima Hospital, Daegu, Korea.
  • 3Department of Neurology, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, Korea. neurojspark@gmail.com

Abstract

Isolated respiratory onset amyotrophic lateral sclerosis (ALS) is a rare clinical manifestation and the diagnosis can be challenging. A 72-year-old man presented with dyspnea and hypercapnia that had started 11 months earlier. A phrenic nerve study was conducted and he was diagnosed promptly with ALS with no significant time delay. The phrenic nerve study is a noninvasive and useful tool in the diagnosis of respiratory onset ALS that can be applied easily in an emergency department.

Keyword

Amyotrophic lateral sclerosis; Dyspnea; Fasciculation; Phrenic nerve study
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