Ann Dermatol.  2012 May;24(2):203-205.

Granular Parakeratosis of Eccrine Ostia

• Yang JH
• Lee HM
• Noh TK
• Won CH
• Chang S
• Lee MW
• Choi JH
• Moon KC

Abstract

Granular parakeratosis is a recently recognized disorder of keratinization that is usually confined to intertriginous areas. The histopathologic features are distinctive and diagnostic. Rarely, histopathologic variants such as follicular granular parakeratosis and granular parakeratosis of eccrine ostia have been described. In this report, we describe a rare case of granular parakeratosis mostly confined to eccrine ostia.

Keyword

Eccrine glands; Neck; Parakeratosis

MeSH Terms

Eccrine Glands
Keratins
Neck
Parakeratosis
Keratins

Figure

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  Fig. 1 (A) Photograph of the patient at the first visit to our clinic in August, showing multiple tiny blackish verrucous papules on the neck. (B) Photograph at the follow-up visit in October, showing disappearance of cutaneous lesions.

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  Fig. 2 Histopathologic examination of a punch biopsy taken from the patient's neck, showing (A) hyperkeratosis and parakeratosis (arrows) (H&E, ×40). (B) Higher magnification showing parakeratotic corneocytes containing multiple basophilic granules (arrows), similar to keratohyaline granules (H&E, ×400). These changes were especially prominent in the stratum corneum of eccrine ostia.

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