Asian Oncol Nurs.  2018 Jun;18(2):104-113. 10.5388/aon.2018.18.2.104.

Relationships among Mood Status, Social Support, Symptom Experience and Quality of Life in Colorectal Cancer Patients - based on the Theory of Unpleasant Symptoms

  • 1Department of Nursing, Inha University Hospital, Incheon, Korea.
  • 2Department of Nursing, Chung-Ang University, Seoul, Korea.
  • 3Department of Nursing, Kyungmin University, Ujeongbu-si, Korea.


This study is to determine the effects of Colorectal Neoplasms patients' stage, location of disease, functional status (physiological factor), mood (psychological factor), and social support (situational factor) on their symptom experience, and to verify the relationship between symptom experience and the quality of life.
The Theory of Unpleasant Symptoms was the framework for the study. A descriptive correlational design was used in analysis of data obtained from a sample of 113 Colorectal Neoplasms patients who were undergoing chemotherapy.
Total mood disturbance and symptom experiences were negatively correlated with physical component score (PCS) and mental component score (MCS) of quality of life (r −.33 to r=−.51, p<.001; r=.40 to r=.50, p<.001). Multiple regression analysis revealed that the functional status and symptoms interference variables explained 29.2% of the variance in PCS of quality of life. Symptoms interference and age explained 30.6% of the variance in MCS of quality of life.
Although overall depression levels were low in this sample, these findings suggest that insomnia and fatigue are related to depression and that depression is more closely associated with quality of life than are insomnia and fatigue.


Colorectal Neoplasms; mood; Social Support; Quality of Life

MeSH Terms

Colorectal Neoplasms*
Drug Therapy
Quality of Life*
Sleep Initiation and Maintenance Disorders


  • Fig. 1. Conceptual framework of this study.

Cited by  1 articles

Factors influencing the health-related quality of life in Korean menopausal women: a cross-sectional study based on the theory of unpleasant symptoms
Ji-Hyun Kang, Moon-Jeong Kim
Korean J Women Health Nurs. 2022;28(2):100-111.    doi: 10.4069/kjwhn.2022.05.29.


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