Korean J Dermatol.
1997 Dec;35(6):1263-1267.
Chronic Cutaneous Lupus Erythematosus in Two Sisters
- Affiliations
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- 1Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
- 2Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Abstract
- Scalp involvements occur in 30-60% of patients with chronic cutaneous lupus erythematosus (CCLE), and may result in irreversible cicartricial alopecia due to follicular destructions. The pathogenesis of CCLE is consiclered to be multifactorial; relevant factors would be immunogenetic, hormonal, and environmental ir fluences. Perhaps, the immunogenetic factors may be more important. We report a case of two sisters who had superficial scarring alopecia on the scalp, in the constitutions of underlying mixed connective tissue disease (MCTD) and undifferentiated connective tissue syndrome (UCTS), respectively. This sister-CCLE case is regarded to be the first report among familial CCLE in Korea.
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