J Korean Orthop Assoc.  1994 Aug;29(4):1136-1141. 10.4055/jkoa.1994.29.4.1136.

Multiple Primary Malignant Neoplasm Combined with Musculoskeletal Malignancy

Abstract

From Jan. of 1990 to Dec. of 1992, we have experienced three cases of multiple primary malignant neoplasms originated from different histogenesis, in the Department of Orthopedic Surgery of Korea Cancer Center Hospital. Liposarcomas, malignant fibrous histiocytoma were combined with renal cell carcinoma, mucinous cystadenocarcinoma of ovary or prostatic cancer. With Moertel's classification, synchronous tumors were found in 2 cases and metachronous in 1 case. Synchronous tumors were 2 liposarcomas-renal cell carcinoma or mucinous cystadenocarcinoma of ovary. Metachronous tumors were malignant fibrous histiocytoma-prostate cancer. We couldn t find any family history among them. The causes of these multiple malignancies were considered as the individual predilrection to tumors.

Keyword

multiple primary malignant neoplasm; musculoskeletal malignancy; synchronous tumors; metachronous tumors

MeSH Terms

Carcinoma, Renal Cell
Classification
Cystadenocarcinoma, Mucinous
Female
Histiocytoma, Malignant Fibrous
Humans
Korea
Liposarcoma
Orthopedics
Ovary
Prostatic Neoplasms
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