Prog Med Phys.  2018 Jun;29(2):73-80. 10.14316/pmp.2018.29.2.73.

Dosimetric Plan Comparison of Accelerated Partial Breast Irradiation (APBI) Using CyberKnife

• Lee CY
• Kim WC
• Kim HJ
• Lee J
• Park S
• Huh HD

• KMID: 2415906
• DOI: http://doi.org/10.14316/pmp.2018.29.2.73

Abstract

Accelerated partial breast irradiation (APBI) is a new treatment delivery technique that decreases overall treatment time by using higher fractional doses than conventional fractionation. Here, a quantitative analysis study of CyberKnife-based APBI was performed on 10 patients with left-sided breast cancer who had already finished conventional treatment at the Inha University Hospital. Dosimetric parameters for four kinds of treatment plans (3D-CRT, IMRT, VMAT, and CyberKnife) were analyzed and compared with constraints in the NSABP B39/RTOG 0413 protocol and a published CyberKnife-based APBI study. For the 10 patients recruited in this study, all the dosimetric parameters, including target coverage and doses to normal structures, met the NSABP B39/RTOG 0413 protocol. Compared with other treatment plans, a more conformal dose to the target and better dose sparing of critical structures were observed in CyberKnife plans. Accelerated partial breast irradiation via CyberKnife is a suitable treatment delivery technique for partial breast irradiation and offers improvements over external beam APBI techniques.

Keyword

APBI; Cyberknife; Treatment planning

MeSH Terms

Breast*
Humans
Unilateral Breast Neoplasms