Ann Dermatol.  2018 Apr;30(2):229-231. 10.5021/ad.2018.30.2.229.

A Case of Angiomatoid Fibrous Histiocytoma Presenting as Subcutaneous Nodule in a 4-Year-Old Girl

Affiliations
  • 1Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. uucm79@hanmail.net

Abstract

No abstract available.


MeSH Terms

Child, Preschool*
Female*
Histiocytoma, Benign Fibrous*
Humans

Figure

  • Fig. 1 (A) A skin colored mass on the right shoulder. (B) Punch biopsy of the lesion showed inflamed pseudocyst with organizing hematoma (H&E, ×40). (C) On magnetic resonance imaging, the tumor shows multiple chambers with fluid level, which is finding of hemangioma or other soft tissue tumors with internal hemorrhage. (D) Ultrasonography reveals increased vascularity of the tumor. (E) The tumor consists of various cells such as round cells or spindle cells with sheet-like or fascicular architecture (H&E, ×100). (F) Multiple aggregates of inflammatory cells are composed mainly of lymphocytes in the periphery of the tumor (H&E, ×40). (G~I) The tumor cells show positive staining for (G) CD68, (H) epithelial membrane antigen, and (I) CD99 (G~I: ×100).


Reference

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2. Enzinger FM. Angiomatoid malignant fibrous histiocytoma: a distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm. Cancer. 1979; 44:2147–2157. PMID: 228836.
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Article
5. Huerter ME, Hammadeh R, Zhou Q, Riker AI. Recurrent angiomatoid fibrous histiocytoma: a case report and review of the literature. Ochsner J. 2014; 14:441–444. PMID: 25249813.
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