J Educ Eval Health Prof.  2016;13:1. 10.3352/jeehp.2016.13.1.

Risk of error estimated from Palestine pharmacists' knowledge and certainty on the adverse effects and contraindications of active pharmaceutical ingredients and excipients

• Shawahna R
• Al-Rjoub M
• Al-Horoub
• Al-Hroub W
• Al-Rjoub B
• Al-Nabi BA

• KMID: 2413750
• DOI: http://doi.org/10.3352/jeehp.2016.13.1

Abstract

PURPOSE
This study aimed to investigate community pharmacists' knowledge and certainty of adverse effects and contraindications of pharmaceutical products to estimate the risk of error. Factors influencing their knowledge and certainty were also investigated.
METHODS
The knowledge of community pharmacists was assessed in a cross-sectional design using a multiple-choice questions test on the adverse effects and contraindications of active pharmaceutical ingredients and excipients from May 2014 to March 2015. Self-rated certainty scores were also recorded for each question. Knowledge and certainty scores were combined to estimate the risk of error.
RESULTS
Out of 315 subjects, 129 community pharmacists (41.0%) completed the 30 multiple-choice questions test on active ingredients and excipients. Knowledge on active ingredients was associated with the year of graduation and obtaining a licence to practice pharmacy. Knowledge on excipients was associated with the degree obtained. There was higher risk of error in items on excipients than those on ingredients (P<0.01).
CONCLUSION
The knowledge of community pharmacists in Palestine was insufficient with high risk of errors. Knowledge of community pharmacists on the safety issues of active ingredients and excipients need to be improved.

Keyword

Cross-sectional studies; Excipients; Palestine; Pharmaceutical services; Risk

MeSH Terms

Cross-Sectional Studies
Excipients*
Humans
Pharmaceutical Preparations
Pharmaceutical Services
Pharmacists
Pharmacy
Excipients
Pharmaceutical Preparations

Figure

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  Fig. 1. Correlation between knowledge scores and certainty for (A) APIs and (B) excipients related questions. APIs, active pharmaceutical ingredients.

Reference

References

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